Acta Oncol Tur.. 2019; 52(2): 262-265 | DOI: 10.5505/aot.2019.08379

Sinonasal Inverted Papillomas

Ayca Ant, Samet Ozlügedýk
UHS Ankara A.Y. Oncology Education and Research Hospital, Otorhinolaryngology, Head and Neck Surgery Department

INTRODUCTION: Inverted papilloma (IP) is the most common epithelial tumor of the sinonasal region. It is crucial for predisposition to the recurrence and malignancy. The incidence of squamous cell carcinoma (SCC) foci is between 5% and 15%. It is usually seen in 5-6th decade and 2 times more frequent in males. It commonly originates from the lateral nasal wall, and secondly from the maxillary sinus. The most common finding is the unilateral nasal obstruction. The treatment is total/wide surgical resection.
METHODS: The patients who underwent surgery with the diagnosis of sinonasal IP between 2007-2017 in a tertiary referral center were included in the study. The patients were evaluated in terms of demographic features, signs and symptoms (clinical and radiological), surgical, pathological features, postoperative complications, and long-term follow-up results.
RESULTS: Twelve of the patients were male (86%), the median age was 56 years (range: 36-79 years). Pathological examination was generally HPV (-), and 4 patients with sinonasal IP (%29) had SCC, in-situ SCC focus, or SCC transformation in the follow-up period.
DISCUSSION AND CONCLUSION: Although inverted papilloma is a benign neoplasm, it is an important disease for malignant content and/or transformation. Consequently, the close follow-up is required for these patients.

Keywords: Nasal diseases, papilloma inverted, paranasal sinuses

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Sinonazal Ýnverted Papillomlar

Ayca Ant, Samet Ozlügedýk
SBÜ Ankara A.Y. Onkoloji Eðitim ve Araþtýrma Hastanesi, Kulak Burun ve Boðaz Hastalýklarý Kliniði

GÝRÝÞ ve AMAÇ: Ýnverted papillom (ÝP), sinonazal bölgenin en sýk epitelyal tümörüdür. Nükse yatkýnlýk ve malignite ile iliþkili olmasý açýsýndan önemlidir. Yassý hücreli karsinom (YHK) odaklarýnýn görülme sýklýðý %5-15 arasýndadýr. Genellikle 5-6. dekatta ve erkeklerde 2 kat daha sýk görülür. En sýk lateral nazal duvardan, ikinci sýklýkta maksiller sinüsten köken alýr. En sýk tek taraflý burun týkanýklýðý ile bulgu verir. Tedavisi total/geniþ cerrahi rezeksiyondur.
YÖNTEM ve GEREÇLER: Sinonazal ÝP tanýsýyla 2007-2017 yýllarý arasýnda bir üçüncü basamak saðlýk merkezinde cerrahi yapýlan hastalar çalýþmaya dahil edildi. Hastalar demografik özellikler, belirti ve (klinik ve radyolojik) bulgular, cerrahi, patolojik özellikleri, cerrahi sonrasý komplikasyonlar ve uzun dönem takip sonuçlarý yönünden deðerlendirildi.
BULGULAR: Hastalarýn 12’si erkek (%86), ortanca yaþ 56 (yaþ aralýðý: 36-79) idi. Patolojik incelemede genel olarak HPV (-) olmakla birlikte, 4 sinonazal ÝP hastasýnda YHK, insitu YHK odaðý veya takipte YHK geliþimi (%29) gözlendi.
TARTIÞMA ve SONUÇ: ÝP, benign bir neoplazi olmasýna raðmen malign içerik ve/veya transformasyon açýsýndan önem arz eden bir hastalýktýr. Sonuç olarak, bu durum hastalarýn yakýn takibini gerektirir.

Anahtar Kelimeler: Nazal hastalýklar, papillom inverted, paranazal sinüsler

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